Researchers discover why cold induces tooth pain and hypersensitivity – and how to stop it

Why do our teeth hurt when it’s cold? Apparently, a gene called TRCP5 is the culprit; it opens up odontoblasts — cells that form a protective layer beneath the enamel — and triggers nerves to fire off the sensation of pain. Researchers found this out by observing two groups of mice with dental injuries; the mice whose genes were edited to remove TRCP5 didn’t display behaviors associated with dental pain. Read full article here


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