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Spinocerebellar ataxia (SCA) is a rare neurodegenerative disease affecting certain geographical areas around the world. The disease arises when rare gene mutations cause the formation of abnormally long chains of proteins which accumulate in the brain and damage the cerebellum; eventually, it causes patients to lose control over their movements. The disease mainly affects areas with groups that practice endogamy — marriage within one’s ethnic group, caste, religion, or other affiliation — like Hindu trader communities, which might explain the higher prevalence of SCA as people marry among themselves. Read full article here

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