Could Cancer Cells’ Iron Addiction Be Their Achilles Heel?

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Ferrous iron-activatable drug conjugates (FeADCs) are drugs that are activated by ferrous iron, and they could be helpful in making anticancer drugs avoid targeting healthy cells. Up to 20% of human cancers have cells that have a higher affinity for a special type of iron called ferrous iron, which seems to be integral to upkeep tumour growth. After making FeADC versions of anti-cancer drugs, researchers observed that the drugs were effective at inhibiting tumour growth and caused no damage to healthy tissue. Read full article here

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The Curious Case of the Ancient Brain

In 2008, archaeologists examining the University of York discovered something strange: the decapitated head of an Iron Age man and his very shrivelled but very much intact brain. How a centuries-old brain was preserved is still unknown, but research suggests that it could have been because of brain diseases like dementia. The Yorkshire man’s brain’s proteins were bunched up together, much like how dementia causes brain proteins to bunch up into plaques. This bunching up, or aggregation, could continue even after death, turning regions of the brain into hard masses. Read full article here


How Are Businesses Responding to Climate Risk?

Overwhelmingly, businesses believe that climate change poses a significant risk involving changes in regulations and consumer demand. However, the majority of them don’t have a formal climate mitigation plan set in place; instead, they’re focusing on stand-alone actions. Some of these include using more energy-efficient equipment, reducing waste and water consumption, and developing more sustainable products. While these actions do help, they’re using them to hit corporate social responsibility goals, not genuinely in the interest of mitigating climate change on a larger scale. Read full article here

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